Shouldn’t we have space colonies by now? Instead there are signs that the pace of technological progress is slowing — even as researchers pump out papers at a prolific and increasing rate. With slowing progress in computing power, medicine and agriculture, my Bloomberg Opinion colleague Noah Smith warns that the stakes could not be higher.
Surely some of the fault lies with technology itself. Our connected world has allowed researchers to become so tightly networked that they’re falling into the trap of groupthink. That might explain why some researchers seeking cures for Alzheimer’s disease, for example, have conceded that they’ve been throwing years of work and billions of
dollars towards a single theory that has failed to lead to any treatment — while ignoring promising alternatives.
Sociologist James Evans of the University of Chicago has concluded that what’s being lost, at least in biomedical research, is scientific independence. Being able to work independently of other labs allows researchers to come up with fresher insights.
Weak studies are not just those that come to the wrong conclusions but those whose conclusions are fragile. If a competitor tries to replicate them, the result will be different, unless conditions and methods are exactly the same. The conclusions of such studies are unlikely to represent broad biological facts, and probably won’t be of much use in medicine.
To sort the weak from the strong, Evans and colleagues were able to use a special case where thousands of studies on the interaction between drugs and genes can be re-tested quickly. A machine can now do what’s called a high throughput assay to rerun a whole slew of previous studies. And so Evans was able to evaluate more than 3,000 published claims against
the results of this mechanical backup, which can not only replay the exact experiments but also test the robustness of the claims by varying the parameters a bit.
Scientists are subject to the same human foibles, but groupthink shouldn’t be conflated with scientific consensus, which is often based on ideas that are backed up by multiple lines of inquiry. What’s rewarded these days is the absolute opposite of those historic claims. While science works best when researchers prove one idea multiple ways, funding agents and journal editors today reward those with only a single line of evidence to support multiple claims. They want bigger claims and are content with lesser evidence.
The technology that’s allowed so much connection has of course also been positive, enabling people to collaborate and learn more efficiently. Researchers can sometimes even counteract extraneous noise by harnessing a wisdom-of-the-crowd phenomenon, where many individuals converge on a right answer. But like many technological changes, it’s come with unintended consequences. The fact that US researchers are producing 1,000 papers a day shows there’s a lot of energy out there to be used more productively —if funding encouraged bold exploration.
—Bloomberg